Table 3.

Estimated diagnostic performance to predict obstructive CAD in clinical practice.

Measure	TP	TN	FP	FN	Sensitivity	Specificity	PPV	NPV	AUC (95%CI)
Ischemia*	76	49	11	14	0.84	0.82	0.87	0.78	0.83 (0.76–0.90)
CAC score†	67	38	22	23	0.74	0.63	0.75	0.62	0.69 (0.60–0.78)
Ischemia_CAC score‡	86	32	28	4	0.96	0.53	0.75	0.89	0.74 (0.66–0.83)

TP = True positive, TN = True negative, FP = False positive, FN = False negative, PPV = Positive Predictive value, NPV = Negative predictive value, *Ischemia = dichotomized with a cut off SDS score of 4 and/or abnormal myocardial bloodflow/coronary flowreserve, †CAC score = coronary artery calcium score as dichotomous variable, <300 or >300. ‡Ischemia_CAC = dichotomized as either ischemia and/or CAC score >300.