Binge Alcohol Induces Left Ventricular Dysfunction
(A) Representative records of left ventricular (LV) pressure and its derivative (dP/dt) in control and alcohol-binged (EtOH 3h) mice, 3 h after maltodextrin or alcohol administration respectively. (B) Representative pressure-volume loops of control and alcohol-binged mice. (C) Systolic indices of LV performance [maximal slope of pressure increment (dP/dtmax), end-systolic pressure, stroke work, stroke volume, cardiac output and ejection fraction] in control (ctrl) and alcohol-binged (EtOH 3h) mice. Data are expressed as mean ± SEM, n = 7 to 8; *p < 0.05 vs. control group.