Table 3.
Association of rs1256328 with nephrolithiasis susceptibility.
| Model | Genotype | Case (%) | TWBa (%) | OR (95% CI) | P value |
|---|---|---|---|---|---|
| Genotypic | TT | 33 (7.5) | 58 (3.9) | 1.87 (1.19–2.92) | 0.0055 |
| CT | 114 (26.0) | 493 (32.7) | 0.76 (0.60–0.97) | 0.0254 | |
| CC | 291 (66.5) | 955 (63.4) | Reference | — | |
| Dominant | TT + CT | 147 (33.5) | 551 (36.6) | 0.88 (0.70–1.10) | 0.2454 |
| CC | 291 (66.5) | 955 (63.4) | Reference | — | |
| Recessive | TT | 33 (7.5) | 58 (3.9) | 2.03 (1.31–3.16) | 0.0013 |
| CT + CC | 405 (92.5) | 1448 (96.1) | Reference | — | |
| Trend test | 0.8313 |
aGeneral population from Taiwan Biobank. P values which remain significant after performing Bonferroni correction (p ≤ 0.016) are shown in bold.