Table 4.
Association of rs12654812 with nephrolithiasis susceptibility.
| Model | Genotype | Case (%) | TWBa (%) | OR (95% CI) | P value |
|---|---|---|---|---|---|
| Genotypic | AA | 39 (8.6) | 68 (4.9) | 1.93 (1.27–2.93) | 0.0019 |
| AG | 160 (37.1) | 523 (37.6) | 1.03 (0.82–1.92) | 0.8191 | |
| GG | 238 (54.3) | 799 (57.5) | Reference | — | |
| Dominant | AA + AG | 199 (45.7) | 591 (42.5) | 1.13 (0.91–1.40) | 0.2664 |
| GG | 238 (54.3) | 799 (57.5) | Reference | — | |
| Recessive | AA | 39 (8.6) | 68 (4.9) | 1.91 (1.27–2.87) | 0.0017 |
| AG + GG | 398 (91.4) | 1322 (95.1) | Reference | — | |
| Trend test | 0.0346 |
aGeneral population from Taiwan Biobank. P values which remain significant after performing Bonferroni correction (p ≤ 0.016) are shown in bold.