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. Author manuscript; available in PMC: 2020 Dec 31.
Published in final edited form as: Biochemistry. 2019 May 22;58(52):5329–5338. doi: 10.1021/acs.biochem.9b00318

Scheme 1. (A) Biosynthesis of Pentabromopseudilin; (B) Deiodination of Human Thyroid Hormonea.

Scheme 1.

a The reaction in (A) proceeds through the debromination activity of Bmp8. The reaction in (B) is catalyzed by deiodinases (Dios).