Table 3.

Cox regression of dementia diagnosis among men (n = 89,251) and women (n = 66,853) with atrial fibrillation HR and with or without levothyroxine treatment in different age-groups in fully adjusted model

	Aged 45–64 years		Aged 65–84 years		Aged 85 + years
	HR	95% CI	HR	95% CI	HR	95% CI
Men
Levothyroxine treatment	1.84	0.68–5.00	1.01	0.84–1.22	0.97	0.71–1.34
No treatment	Ref		Ref		Ref
Women
Levothyroxine treatment	0.71	0.26–1.95	1.06	0.95–1.18	0.99	0.86–1.14.
No treatment	Ref		Ref		Ref
Alla
Levothyroxine treatment	1.05	0.51–2.15	1.05	0.95–1.15	0.99	0.87–1.13
No treatment	Ref		Ref		Ref

Full Model adjusted for age, educational level, immigrant status, marital status, neighborhood deprivation, comorbidities, and cardiovascular medications

^aGender was added in the fully adjusted model