Fig. 8:

Schematic diagram of the principal pathways involved in cerebellar outflow tremor. Tremor is initiated by cortical activation of the agonist muscles. The descending cortical command is also transmitted to the interpositus (IP) and associated spinocerebellar cortex via the pontine nuclei. IP nucleus projects back to the cerebral cortex via the ventrolateral thalamus. This corticobulbocerebellothalamocortical loop ② is an important avenue for feedforward motor control. Absent feedforward control, the nervous system relies excessively of feedback control ① based on sensory feedback from the musculoskeletal system. Interpositus and spinothalamic fibers have overlapping projections to the ventrolateral thalamus (VL).