5. Patient outcomes: adjusted and subgroup analyses of secondary outcomes.

Outcome	Adjusted analysis/Factor considered	Time point (months)	Mean difference	95% confidence Interval	Participants (N)	Heterogeneity (%)	Certainty of evidence	Figure number
SF‐36 QoL physical domain	Breast and prostate cancer	6	2.2	‐4.62 to 9.02	168	NA	Very low	Analysis 4.4
	Breast and prostate cancer	12	‐0.20	‐7.42 to 7.02	160	NA	Very low	Analysis 4.4
SF‐36 QoL mental health domain	Breast cancer	12	‐4.3	‐9.96 to 1.09	40	NA	Very low	Analysis 4.7
	Colorectal cancer	12	‐0.7	‐2.64 to 1.24	410	NA	Low	Analysis 4.7
	Breast, prostate, and colorectal cancer	12	7.04	5.25 to 8.83	641	NA	Low	Analysis 4.7

NA: not applicable.

QoL: quality of life.

SF‐36: Short Form‐36.