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The rare adverse event called reversible posterior leukoencephalopathy syndrome. a, b Brain MRI showed a posterior periventricular white matter hyperintensity and a signal alteration of the white matter interior of the cerebellum, confirming the diagnosis of toxic encephalopathy. c, d Brain MRI performed after 2 weeks of lenvatinib withdrawal documented an almost complete resolution of the radiological alterations, allowing to re-introduce the MKI.
