Table 1.

Parameters to be evaluated at baseline and at each control visit

	Parameters to be evaluated
Clinical data	Weight, appetite, fatigue, diarrhoea, skin manifestations, patient's diary on side effects and/or symptoms
Blood tests	TSH, fT4 (thyroglobulin, Tg antibodies at periodical intervals) Electrolytes (Ca, Na, K, Mg) Full blood count ALT, ALP, GGT Glucose, total HDL, LDL cholesterol, triglycerides
Cardiac parameters	ECG (QTc interval) Blood pressure
Imaging	Whole-body imaging (CT scan with contrast medium and/or MRI and/or18-FDG-PET/CT scan) (first visit, then periodical evaluation metastatic sites) Bone scintigraphy (optional)