Table 2.
Baseline characteristics categorized by TCF7L2 genotype
| CT (n = 32) | CC (n = 385) | TT (n = 5) | p value | |
|---|---|---|---|---|
| Male | 17 (53.1) | 187 (48.9) | 1 (20) | 0.312 |
| Age, years | 58.1 ± 10.3 | 62.3 ± 11.8 | 66.0 ± 9.3 | 0.110 |
| RAAS blockage | 20 (62.5) | 267 (69.7) | 3 (60) | 0.634 |
| Aspirin | 24 (75) | 317 (82.3) | 4 (80) | 0.540 |
| Comorbid diseases | ||||
| Hypertension | 30 (93.7) | 366 (95.0) | 5 (100) | 0.830 |
| Dyslipidemia | 28 (87.5) | 372 (96.6) | 5 (100) | 0.037 |
| Cardiovascular disease | 3 (9.38) | 57 (14.8) | 3 (60) | 0.012 |
| Clinical findings | ||||
| Systolic blood pressure, mm Hg | 133.5 ± 5.9 | 134.8 ± 5.8 | 139.8 ± 1.5 | 0.076 |
| Diastolic blood pressure, mm Hg | 82.2 ± 5.1 | 82.3 ± 5.4 | 84.2 ± 6.5 | 0.726 |
| Laboratory findings | ||||
| Fasting plasma glucose, mg/dL | 140.2 ± 38.9 | 135.9 ± 45.6 | 123.4 ± 24.8 | 0.713 |
| Hemoglobin A1c, % | 7.2 ± 1.8 | 7.2 ± 1.3 | 7.3 ± 1.1 | 0.986 |
| LDL, mg/dL | 106.7 ± 37.4 | 105.9 ± 50.8 | 131.4 ± 38.1 | 0.525 |
| Estimated GFR, mL/min/1.73 m2 | 72.3 ± 31.8 | 72.8 ± 24.4 | 87.0 ± 20.0 | 0.526 |
Data are presented as mean ± SD orn (%), as appropriate. RAAS blockage, renin angiotensin aldosterone system blockage; LDL, low-density lipoprotein; GFR, glomerular filtration rate.