Table 1.
Histopathologic classification of tumors arising in response to ectopic β-catenin expression
| Mutant | Associated tumor histologya | Growth rate group (from Fig. S1A) |
|---|---|---|
| S33A | CF + MT + BL | 1 |
| S33Y | PF + CF + MT + HCC | 2 |
| S37A | CF + PF + HCC | 2 |
| T41A | HCC + PL + MT | 2 |
| S45A | CF | 1 |
| S45F | CF + PF | 2 |
| S45P | MT ± PF ± BL | 2 |
| K335I | HCC ± BL | 1 |
| N387K | CF ± PF ± BL | 1 |
| R582W | HCC | 3 |
| Δ(20–32) | CF + BL | 1 |
| Δ(36–53) | CF + PF + HCC | 3 |
| Δ(45–58) | CF ± PF | 2 |
| Δ(90) | CF | 1 |
| WT | HCC ± CF | 3 |
a CF, crowded fetal; MT, macrotrabecular; BL, blastemal; PF, pleomorphic fetal; HCC, hepatocellular carcinoma. In cases where multiple histologic subtypes were observed, the most prominent one is listed first.