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The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2019 Nov 15;294(46):17707. doi: 10.1074/jbc.AAC119.011523

Correction: Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.

Jeremy J Ryan, Macy L Sprunger, Kayla Holthaus, James Shorter, Meredith E Jackrel
PMCID: PMC6873207  PMID: 31732685

VOLUME 294 (2019) PAGES 11286–11296

Throughout the text, the abbreviations “EWS-FLI1” and “EWS-FLI3” refer to EWS-FLI1, type 1 and EWS-FLI1, type 3, respectively. These are EWS-FLI1 fusion proteins that arise from slightly different chromosomal translocations that are found naturally in human sarcomas (1). Domain maps for these distinct fusion proteins are shown in Fig. 2A.

Reference

  • 1. Gonzalez I., Vicent S., de Alava E., and Lecanda F. (2007) EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model. J. Mol. Med. (Berl.), 1015–1029 10.1007/s00109-007-0202-5 [DOI] [PubMed] [Google Scholar]

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