VOLUME 294 (2019) PAGES 11286–11296
Throughout the text, the abbreviations “EWS-FLI1” and “EWS-FLI3” refer to EWS-FLI1, type 1 and EWS-FLI1, type 3, respectively. These are EWS-FLI1 fusion proteins that arise from slightly different chromosomal translocations that are found naturally in human sarcomas (1). Domain maps for these distinct fusion proteins are shown in Fig. 2A.
Reference
- 1. Gonzalez I., Vicent S., de Alava E., and Lecanda F. (2007) EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model. J. Mol. Med. (Berl.), 1015–1029 10.1007/s00109-007-0202-5 [DOI] [PubMed] [Google Scholar]
