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. 2019 Nov 15;10:2642. doi: 10.3389/fmicb.2019.02642

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Copyright © 2019 Bonifácio, Vila, Masiero, da Silva, da Silva, de Oliveira Lopes, dos Santos Ramos, de Souza, Vilegas, Pavan, Chorilli, Lopez-Ribot and Bauab.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fungal loads detected in vaginal lavages from animals in different experimental and control groups on days 0, 2, 4, 6, and 8 of treatment. ME, microemulsion. Different letters in superscripts in columns indicate statistically significant differences (P < 0.05) according to two-way ANOVA with post-test Tukey. ^aComparison between the free extract and the DMSO control. ^bComparison between the loaded extract and the microemulsion control. ^cComparison between the loaded and the free extract. ^∗Undetectable fungal burden for the animals treated with the free extract (days 6 and 8) and the loaded extract (days 4, 6, and 8).