Table 2.
Clinical profile of patients with 5α-reductase type-2 deficiency
| Age at presentation | Consanguity | Clinical phenotype | HCG stimultated T/DHT ratio |
|---|---|---|---|
| 2 months | Yes | Penoscrotal hypospadias | 31.9 |
| 1 month | Yes | Micropenis; Penoscrotal hypospadias | 21.2 |
| Birth | Yes | Bifid scrotum; Perineal hypospadias | 36.8 |
| 3 months | Yes | Bifid scrotum; Penoscrotal hypospadias | 30.2 |
| 4 years | No | Bifid scrotum; Penoscrotal hypospadias | 26.0 |
| 2 day | No | Bifid scrotum; Perineal hypospadias | 42.0 |
| Birth | No | Penoscrotal hypospadias | 52.8 |
| 1 month | Yes | Micropenis; Bifid scrotum | 71.0 |
| 13 years | Yes | Penoscrotal hypospadias | 65.2 |
| 3 months | Yes | Micropenis; Penoscrotal hypospadias | 75.4 |
| Birth | No | Penoscrotal hypospadias | 47.4 |
| Birth | No | Micropenis; Penoscrotal hypospadias | 54.0 |
| 13 years | No | Bifid scrotum; Perineal hypospadias | 25.0 |
| 1 year and 6 months | Yes | Micropenis; Penoscrotal hypospadias | 33.6 |
| 3 months | No | Micropenis; Perineal hypospadias; Bifid scrotum | 55.5 |
| 2 years | No | Micropenis; Penoscrotal hypospadias | 27.3 |
| Birth | Yes | Micropenis; Bifid scrotum | 29.8 |
HCG: Human chorionic gonadotropin; T: Testosterone; DHT: Dihydrotestosterone