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. 2019 Oct 3;30(11):2715–2726. doi: 10.1021/acs.bioconjchem.9b00588

Figure 1.

Figure 1

Carbohydrate–protein interactions play a myriad of roles in the immune system. They influence initial pattern recognition, leading to immune activation, as well as the routing of immune cells in the body to immune suppressive effects. They can also be targets of antibody responses, leading to clearance of specific glycans. All these events can affect others in the pathway either synergistically or detrimentally.