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Homopentamer might be the functional format of Nell-1. The predicted 3-dimensional structure of Nell-1 as a homodimer (A), homotrimer (B), and homopentamer (C) and that of the Nell-1 pentamer and Cntnap4 complex (D) were predicted by using the PATCHDOCK server (http://bioinfo3d.cs.tau.ac.il/PatchDock/php.php) and I-TASSER server (https://zhanglab.ccmb.med.umich.edu/I-TASSER/).
