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. 2019 Nov 15;10:2688. doi: 10.3389/fimmu.2019.02688

Figure 1.

Figure 1

NK cells are major producers of IL-10 during the initial stages of MCMV infection. IL-10-GFP mice were either uninfected or challenged with 3,000 PFU MCMV i.p. and the peripheral blood leukocytes were analyzed on the indicated days. (A) The overlay plots depict IL-10-GFP expression in NK cells and T cells in the peripheral blood of uninfected (D0) and infected (D4) mice. (B) Back gating analysis representing IL-10 producing NK cells and T cells among total IL-10-GFP expressing cells. (C,D) The graphs represent the complete kinetics of IL-10-GFP expression throughout the course of MCMV infection. The proportion and number of IL-10-GFP expressing NK cells and T cells are obtained from total peripheral blood leucocytes (n = 3; two experiments). Data represent mean + SD.