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TnSeq datasets in different antibiotic treatments
| Drug | Concentration (μg/ml) | MIC50 (μg/ml) | Number of replicates | Number of essentials vs. untreateda |
|---|---|---|---|---|
| Untreated | 3 | |||
| Isoniazid (INH) | 0.027 | 0.04 | 2 | 50 |
| Rifampicin (RIF) | 0.004 | 0.02 | 3 | 68 |
| ethambutol (EMB) | 0.5 | 0.6 | 3 | 58 |
| Meropenem (MER) | 1.2 | 30 | 3 | 106 |
| Vancomycin (VAN) | 16 | 11 | 3 | 93 |
MICs for H37Rv were obtained from [43]
aNumber of conditional essentials by comparison to the untreated condition using resampling
