Fig. 1.

Inhibition of miR-30b-5p expression in hypoxic cardiomyocytes. a AC16 cells were exposed to hypoxia for 6, 12 and 24 h, respectively, and then harvested for analysis by quantitative real-time PCR. b The expression of miR-30b-5p was determined in AC16 cells transfected with miR-30b-5p inhibitor or NC, followed by 12 h hypoxia treatment. Cells cultured under normoxia were used as the control. *: hypoxia vs. normoxia; #: hypoxia + inhibitor vs. hypoxia + NC; **p < 0.01, ***p < 0.001, ##p < 0.01