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. 2019 Nov 21;12:48. doi: 10.1186/s13039-019-0459-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Foetal abnormality detection in prenatal samples. In total, 200 prenatal samples (amniotic fluid and CVS) were subjected to prenatal diagnosis using the same single comprehensive assay. All normal and abnormal samples were correctly classified. The x-axis denotes the targeted chromosomes (chr 13, 18, 21, X). The y-axis represents the normalized read depth per TACS (dots). Red dots denote positive calls. The panels show the detection of a Trisomy 21, b Monosomy X, c Trisomy 13, d Trisomy 18