Table 2.
Characteristics of Stenotrophomonas maltophilia hospital-acquired pneumonia
| Variables | Total N = 282 |
|---|---|
| Monomicrobial pneumonia (S. maltophilia only) (n, (%)) | 117 (41.6) |
| Other microorganisms identified (polymicrobial) (n, (%)) | |
| Acinetobacter baumanii | 7 (4.3) |
| Citrobacter spp. | 7 (4.3) |
| Enterobacter spp. | 30 (18.3) |
| Enterococcus spp. | 6 (3.7) |
| Escherichia coli | 25 (15.2) |
| Haemophilus | 3 (1.8) |
| Hafnia alvei | 3 (1.8) |
| Klebsiella spp. | 25 (15.2) |
| Methicillin-resistant Staphylococcus aureus | 3 (1.8) |
| Methicillin-sensitive Staphylococcus aureus | 13 (7.9) |
| Morganella morganii | 1 (0.6) |
| Proteus spp. | 7 (4.3) |
| Pseudomonas aeruginosa | 49 (29.9) |
| Serratia spp. | 8 (4.9) |
| Streptococcus spp. | 1 (0.6) |
| Others | 10 (6.1) |
| S. maltophilia pneumonia-related manifestations (n, (%)) | |
| Associated bacteremia | 20 (7.1) |
| Associated empyema thoracis | 25 (8.9) |
| Associated septic shock | 123 (43.6) |
| Total number of days of norepinephrine infusion (median [IQR]) | 0 [0–6] |
| Severity of pneumonia | |
| Oxygenation level regarding S. maltophilia HAP (n, (%)) | |
| Hypoxemia with PaO2/FIO2 > 300 mmHg with PEEP ≥ 5 cmH2O | 45 (16) |
| Mild ARDS | 98 (34.7) |
| Moderate ARDS | 101 (35.8) |
| Severe ARDS | 36 (12.7) |
| Prone positioning (n, (%)) | 13 (4.6) |
| ECMO requirement | 15 (5.3) |
| Veno-venous | 8 (53.3) |
| Veno-arterial | 7 (46.7) |
Data is presented as number (%) or median [IQR]. Mild ARDS (200 mmHg < PaO2/FiO2 ≤ 300 mmHg with PEEP ≥ 5 cmH2O), moderate ARDS (100 mmHg < PaO2/FiO2 ≤ 200 mmHg with PEEP ≥ 5 cmH2O), severe ARDS (PaO2/FiO2 ≤ 100 mmHg with PEEP ≥ 5 cmH2O)
S. maltophilia, Stenotrophomonas maltophilia; ARDS, Acute Respiratory Distress Syndrome, was defined according to the Berlin definition; PEEP, positive end-expiratory pressure