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. 2019 Nov 21;19:1137. doi: 10.1186/s12885-019-6347-0

Table 1.

Relationship between molecular profiles and the pathologic factors

Grade 1,2/3,4 p value pT1,2/3,4 p value pN0/1,2 p value
(n = 14/36) (n = 13/37) (n = 32/18)
Mutation (+) of Nrf2 (n = 5) 1 / 4 0.7471 0 / 5 0.1624 3 / 2 0.9687
No mutation of Nrf2 (n = 45) 13 / 32 13 / 32 29 / 16
C/C at rs6721961 (n = 30) 8 / 22 0.7975 8 / 22 0.8953 19 / 11 0.4915
C/A or A/A at rs6721961 (n = 20) 6 / 14 5 / 15 13 / 7
Nrf2 Low (n = 26) 8 / 18 0.6499 10 / 16 0.0365 19 / 7 0.1988
Nrf2 High (n = 24) 6 / 18 3 / 21 13 / 11
Mutation (+) of Keap1 (n = 11) 1 / 10 0.1477 1 / 10 0.1477 6 / 5 0.2928
No mutation of Keap1 (n = 39) 13 / 36 12 / 27 26 / 13