Table 3.
CR/PR/SD > 12w* (n = 26) | SD < 12w/PD* (n = 24) | p value | |
---|---|---|---|
Mutation of Nrf2 | |||
(+) (n = 5) | 0 | 5 | 0.0142 |
(−) (n = 45) | 26 | 19 | |
SNPs at rs6721961 | |||
C/C (n = 30) | 21 | 9 | 0.0018 |
C/A or A/A (n = 20) | 5 | 15 | |
Nrf2 expresion | |||
Low (n = 26) | 21 | 5 | < 0.0001 |
High (n = 24) | 5 | 19 | |
Mutation of Keap1 | |||
(+) (n = 11) | 6 | 5 | 0.8783 |
(−) (n = 39) | 20 | 19 |
CR/PR/SD > 12w* Complete response, partial response, or stable disease for > 12 weeks
SD < 12w/PD* Stable disease for < 12 weeks or progressive disease