Table 1.
Patients (n = 13) | |
Median age (range) | 69 years (42–87) |
Male/female | 3/10 |
Histology | |
Papillary cancer | 3 |
Follicular cancer | 9 |
Poorly differentiated cancer | 1 |
TNM stage* at the time of initial surgery | |
II | 3 |
III | 3 |
IVA | 2 |
IVC | 4 |
Unknown | 1 |
Distant metastases other than bone metastases at the time of SRT | |
Nothing | 7 |
Lung | 2 |
Lung and brain | 2 |
Liver | 1 |
Lung, brain and pancreas | 1 |
Median duration from initial surgery to SRT (range) | 52 months (1–380) |
Previous treatment | |
RAI therapy yes/no | 10/3 |
(range of cumulative dose) | (1110–18 870 MBq) |
Surgery yes/no | 2/11 |
EBRT yes/no | 2/11 |
TKI treatment yes/no | 1/12 |
Number of treated lesions per patient | |
1 | 4 |
2 | 3 |
3 | 1 |
4 | 2 |
9 | 1 |
29 | 1 |
Lesions (n = 60) | |
Site of lesion | |
Skull | 2 |
Cervical spine | 7 |
Thoracic spine | 11 |
Lumbar spine | 10 |
Ribs | 10 |
Scapula | 5 |
Pelvis | 11 |
Others** | 4 |
Median size of lesions (range) | 21 mm (5.5–70) |
Symptoms caused by bone metastasis yes/no | 7/53 |
Median number of fractions (range) | 3 fx (1–10) |
Median dose of SRT (range) | 27 Gy (8–48) |
*TNM Classification of Malignant Tumours 7th ed, SRT=stereotactic radiotherapy, RAI=radioactive iodine, EBRT=external beam radiotherapy, TKI=tyrosine kinase inhibitor.
**Others include hyoid, clavicles and sternum.