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. 2019 Nov 21;10:344. doi: 10.1186/s13287-019-1458-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — LncRNA HIT regulates mesenchymal stem cells through LncRNA DA125942, ROCR, and slincR which influence the expression of SOX9 which is important in the early stage of chondrocyte differentiation. LncRNA ZBED-AS1, H19, and CTA-941F9.9 are involved in the process of chondrocyte differentiation. LncRNA RMRP could promote the chondrocyte differentiating to hypertrophic chondrocytes