Fig. 3.

Effects of ALM16 on the activities of MMP-1, − 3 and − 13 in IL-1β-induced SW1353 cells. a MMP-1, (b) MMP-3 and (c) MMP-13 levels. Cells were pre-treated with A, L and ALM16 for 30 min and then further treated with IL-1β for 24 h. The content of MMPs in the cell supernatant was detected using a commercial ELISA kit method. The results are expressed as the mean ± S.E.M of triple experiments. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001 compared with IL-1β-treated control cells