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. 2019 Nov 21;19:325. doi: 10.1186/s12906-019-2746-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effects of ALM16 on the GAG content in IL-1β-induced SW1353 alginate bead cells. Cells were pre-treated with A, L and ALM16 for 30 min and then further treated with IL-1β for 48 h. The GAG content in the cell supernatant was detected using a GAG assay kit. The results are expressed as the mean ± S.E.M of triple experiments. ^***p < 0.001 compared with IL-1β-treated control cells