Fig. 6.

Anti-edematous effect of ALM16 on carrageenan-induced paw edema in mice. Edema thickness was measured 1 h after the 1% carrageenan injection. a Injection of A, L and ALM16 (400 mg/kg b.w.) or celecoxib (100 mg/kg b.w.). b Injection of ALM16 in a dose dependent manner. The results are expressed as the mean ± S.E.M (n = 8). Data were analyzed by one-way ANOVA Tukey’s test to compare all of the tested groups. ^#p < 0.05, ^##p < 0.01, ^###p < 0.01 and ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 compared with the control group at 3 and 5 h after 1% carrageenan injection, respectively