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. 2019 Nov 21;19:325. doi: 10.1186/s12906-019-2746-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Histopathological changes of articular cartilage the femoral-tibial knee joint from MIA-induced OA rat. Wister rats were subjected to intra-articular injection of MIA (1 mg/animal) and fed orally with or without samples daily for 2 weeks. a Histological sections (× 200) were stained with hematoxylin & eosin (H&E) staining. b Histopathological changes are quantitatively expressed by arthritis scoring. The results are expressed as the mean ± S.E.M. Data were analyzed by one-way ANOVA Tukey’s test to compare all of the tested groups. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 compared with the MIA-induced control group