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. Author manuscript; available in PMC: 2019 Nov 22.
Published in final edited form as: Am J Transplant. 2019 May 14;19(9):2421–2433. doi: 10.1111/ajt.15376

FIGURE 1.

FIGURE 1

Immunosuppression (IS) treatment promoted mouse cytomegalovirus (MCMV) reactivation and systemic dissemination after D+-to-R– allogeneic transplants (allografts). Viral DNA in kidneys, lungs, and salivary glands (SGs) were quantified by quantitative PCR at postoperative days (POD)7-28 after allogeneic vascularized transplantation of D+ kidneys from B6 mice into R– BALB/c recipients (n = 5-6/ time/group). A, Schematic of experimental setup. B, Viral DNA copy numbers in kidneys at POD0 (donor contralateral controls) and the kidney allografts treated with IS (w/IS) or without IS (wo/IS) at PODs 7, 14, and 28. C, Viral DNA copy numbers in recipient lungs (r-lung) and salivary gland (r-sg) from transplant recipients at PODs 7, 14, and 28