Table 3.

Univariate and multivariate analyses for disease-free survival

Variables	Univariate analysis				Multivariate analysis
	HR	95% CI	P		HR	95% CI	P
Age	0.856	0.554–1.322	0.482
Sex	0.614	0.314–1.203	0.155
AFP	1.005	0.633–1.595	0.984
Cirrhosis	1.278	0.742–2.204	0.377
Tumor size, cm	1.130	1.066–1.526	0.022		1.012	1.008–1.479	0.035
Differentiation	1.602	0.816–3.144	0.816
TNM stage	1.022	0.555–1.884	0.555
Vascular invasion	1.869	1.004–3.512	0.002		1.824	1.004–3.194	0.007
PAR2 expression	1.007	1.003–1.462	0.030		1.002	1.002–1.521	0.032

Abbreviations: PAR2 proteinase activated receptor 2, AFP alpha-fetoprotein