Table 4.
Univariate and multivariate analyses for recurrence
| Variables | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | ||
| Age | 0.929 | 0.586–1.471 | 0.752 | ||||
| Sex | 0.624 | 0.307–1.269 | 0.193 | ||||
| AFP | 0.863 | 0.536–1.391 | 0.546 | ||||
| Cirrhosis | 1.182 | 0.679–2.057 | 0.555 | ||||
| Tumor size, cm | 0.985 | 0.583–1.663 | 0.955 | ||||
| Differentiation | 1.379 | 0.694–2.737 | 0.359 | ||||
| TNM stage | 1.096 | 0.566–2.122 | 0.786 | ||||
| Vascular invasion | 1.919 | 1.069–3.696 | 0.001 | 1.827 | 1.051–2.885 | 0.026 | |
| PAR2 expression | 1.057 | 1.005–1.631 | 0.032 | 1.048 | 1.002–1.379 | 0.048 | |
Abbreviations: PAR2 proteinase activated receptor 2, AFP alpha-fetoprotein