Table 3.
Univariate analysis of clinical characteristics of asthmatic children associated with neuropsychiatric comorbidities (n, %)
| Variables | Category | AWNC (n = 69) |
AONC (n = 192) |
χ2 | P |
|---|---|---|---|---|---|
| Onset of asthma | ≤3 years | 44(63.8) | 105(54.7) | 1.709 | 0.191 |
| >3 years | 25(36.2) | 87(45.3) | |||
| Severity of asthma | Severe persistent | 13(18.8) | 13(6.8) | 8.244 | 0.004 |
| Mild persistent | 56(81.2) | 179(93.2) | |||
| Asthma control level | Poor control | 40(58.0) | 71(37.0) | 9.151 | 0.002 |
| Good control | 29(42.0) | 121(63.0) | |||
| Anti-asthmatic drug usage | ICS | 16(23.2) | 15(7.8) | 10.04 | 0.001 |
| LTRA | 4(5.8) | 18(9.4) | 0.471 | 0.493 | |
| LTRA+ICS | 10(14.5) | 45(23.4) | 1.933 | 0.164 | |
| BA+ICS | 6(8.7) | 17(8.9) | 0.043 | 0.835 | |
| BA+ICS + LTRA | 33(47.8) | 97(50.5) | 0.003 | 0.958 | |
| Anti-asthmatic therapy | Monotherapy | 20(29.0) | 33(17.2) | 4.366 | 0.037 |
| Multidrug therapy | 49(71.0) | 159(82.8) | |||
| Regular follow-up | Yes | 40(58.0) | 105(54.7) | 0.222 | 0.638 |
| No | 29(42.0) | 87(45.3) | |||
| Family history | Yes | 18(26.1) | 43(22.4) | 0.386 | 0.534 |
| No | 51(73.9) | 149(77.6) | |||
| Asthma attacks | ≥1 time monthly | 8(11.6) | 20(10.4) | 7.034 | 0.071 |
| ≥ every 3 months, < 1 time monthly | 32(46.4) | 60(31.2) | |||
| ≥ every 6 months, < 1 time every 3 months | 16(23.2) | 75(39.1) | |||
| No attack ≥1 year | 13(18.8) | 37(19.3) | |||
| Duration | > 3 years | 50(72.5) | 90(46.9) | 13.365 | 0.000 |
| ≤3 years | 19(27.5) | 102(53.1) |
AWNC Asthma with neuropsychiatric comorbidities, AONC Asthma without neuropsychiatric comorbidities, ICS Inhaled corticosteroid, LTRA Leukotriene receptor agonists, BA Beta-2-agonists