Table 2.
Classical respiratory mechanics parameters
| PEEP 5 cmH2O | PEEP 15 cmH2O | p value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Inspiratory flow | Inspiratory flow | Flow | PEEP | Interaction | |||||
| Low | Medium | High | Low | Medium | High | ||||
| Ppeak, cmH2O | 21*,† [19–24] | 28† [23–33] | 39 [34–45] | 31*,† [28–33] | 36† [35–41] | 47 [44–51] | <0.001 | <0.001 | <0.001 |
| P1, cmH2O | 17† [15–20] | 17 [16–19] | 18 [17–20] | 27 [25–29] | 28 [26–29] | 28 [26–31] | 0.007 | <0.001 | 0.889 |
| Pplat, cmH2O | 15 [15–18] | 15 [14–16] | 15 [14–16] | 26 [24–26] | 25 [23–26] | 26 [24–27] | 0.262 | <0.001 | 0.568 |
| PEEPtot, cmH2O | 6† [5–7] | 6 [5–6] | 5 [5–6] | 16*,† [15,16] | 15 [15–15] | 15 [15–15] | 0.003 | <0.001 | 0.442 |
| Driving P, cmH2O | 10 [8–11] | 9 [8–11] | 10 [8–11] | 10 [9–11] | 10 [8–11] | 10 [9–12] | 0.017 | 0.539 | 0.455 |
Ppeak peak airway pressure, P1 end-inspiratory airway pressure at 0 flow, Pplat end-inspiratory plateau airway pressure, PEEPtot total (set + intrinsic) positive end-expiratory pressure, Driving P driving airway pressure
*p < 0.05 vs medium inspiratory flow; †p < 0.05 vs high inspiratory flow