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. 2019 Nov 15;7:320. doi: 10.3389/fbioe.2019.00320

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Copyright © 2019 Yang, Wang, Wan, Gu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Schematic illustration of construction of theranostic Ag₂S nanodots in HSA Nanocages. (B) Fluorescence spectra of Ag₂S-NDs. (C) Temperature elevations of Ag₂S-NDs under 5 min irradiation (785 nm, 1.5 W cm⁻²). (D) Biodistribution of Ag₂S-NDs at 24 h post-injection. (E) NIR fluorescence imaging of 4T1-tumor-bearing mice treated with Cy7.5-labeled Ag₂S-NDs at 72 h post-injection. (F) Long-term distributions of Ag₂S-NDs in various major tissues during 30 days post-injection. Dose: 50.0 μmol kg⁻¹ Ag.