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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Int J Hyperthermia. 2019;36(1):1084–1097. doi: 10.1080/02656736.2019.1679893

Fig.9.

Fig.9

shows the time in range (TIR) estimates based on various combinations of breath-hold and freebreathing periods. Panel A shows examples of the heating profile in time for different combinations. At a fixed free-breathing period, shorter breath-hold period generated less heating effect and shorter TIR (first and second row). On the other hand, with a fixed breath-hold period, longer free-breathing period resulted in a shorter TIR (first and third row). Panel B depicts a contour map of TIR for various combinations of breath hold and free breathing duration for a 10-minutes hyperthermia treatment. Contour lines indicate the suggested combination to achieve a TIR of 7, 8, and 9 minutes, respectively.