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. 2019 Nov 15;10:1215. doi: 10.3389/fneur.2019.01215

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Copyright © 2019 Jing, Yang, Fu, Wang, Yang, Yuan, Chen, Ding, Chen and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serpina3k improved neurological function in mice following TBI. mNSS (A) and rotarod test results (B) at 1, 3, 7, and 14 days post-TBI in the TBI+vehicle and TBI+A3K groups. Representative traces (C,E), and quantified time of first arrival at the platform (D) and percentage of time spent in the target (platform) quadrant (F) at 19 days after TBI in the sham, TBI+vehicle, and TBI+A3K groups. Data represent the mean ± SD (n = 12 per group). *P <0.05, **P <0.01, TBI+A3K group vs. TBI+vehicle group.