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. 2019 Nov 15;10:2669. doi: 10.3389/fmicb.2019.02669

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Copyright © 2019 Roselletti, Monari, Sabbatini, Perito, Vecchiarelli, Sobel and Cassone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlated expression of C. albicans genes. Vaginal samples of symptomatic women were centrifuged at 3,000 rpm for 10 min, then cellular fractions were lysed, and total RNA was extracted and retro-transcribed to cDNA. (A–F) The expression levels of SAP2, SAP6, ECE1, and HWP1 genes were calculated by comparative Ct method (2^−∆Ct formula) after normalization with ACT1 gene. The results reported are from triplicates samples from 40 VVC subjects. Linear regression lines are shown. Pearson correlation (r) and statistical significance are indicated in each panel.