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. 2019 Nov 15;10:1418. doi: 10.3389/fphys.2019.01418

TABLE 3.

Effect of dietary supplementation with organic acids in drinking water or in feed on the intestinal mucosal morphology of broilers exposed to Salmonella Pullorum challenge at 42 days.

Items Unchallenge control Challenge control Challenge + VGd Challenge + OAe water Challenge + OAe feed Challenge + OAe water + OAe feed P-value
Jejunum
Villus height (μm) 1129.06 ± 237.24 1079.13 ± 81.93 1172.93 ± 223.76 1197.85 ± 77.19 1026.28 ± 76.94 1078.86 ± 125.83 0.437
Crypt depth (μm) 237.04 ± 23.48b 293.6 ± 28.26a 245.32 ± 13.30b 221.78 ± 22.40b 224.76 ± 55.12b 242.94 ± 31.40b 0.008
Villus height:crypt depth ratio 4.54 ± 0.49bc 3.87 ± 0.31c 4.78 ± 0.84ab 5.55 ± 0.68a 4.37 ± 0.70bc 4.49 ± 0.64bc 0.011
Ileum
Villus height (μm) 729.28 ± 81.61 704.28 ± 165.84 739.28 ± 194.71 796.85 ± 217.51 804.32 ± 97.68 748.4 ± 139.04 0.888
Crypt depth (μm) 195.3 ± 25.35 220.42 ± 45.58 208.02 ± 60.91 219.53 ± 35.15 195.57 ± 21.71 203.83 ± 32.19 0.786
Villus height:crypt depth ratio 3.77 ± 0.48 3.67 ± 0.45 3.60 ± 0.61 3.60 ± 0.57 4.15 ± 0.67 3.68 ± 0.40 0.497

acMeans within a row with no common superscript differ significantly (n = 8; P < 0.05). Data are means of eight replicates of a bird per replicate pen. dVG, virginiamycin feed grade premix. eOA, organic acids.