TABLE 3.
Transcription factors predicted by iRegulon.
| Upregulated proteins (TG.NT-WT.NT) | Downregulated proteins (TG.NT-WT.NT) | ||||
| Transcription factor | Targets | NES | Transcription factor | Targets | NES |
| Srf | 10 | 5.1 | Msx1 | 17 | 5.1 |
| Cebpa | 8 | 4.7 | Nkx2-2 | 13 | 4.9 |
| Arntl | 9 | 4.5 | Ddx43 | 10 | 4.7 |
| Nr2c2 | 10 | 4 | Tcf3 | 10 | 4.6 |
| Smc3 | 20 | 4.6 | |||
| Foxo1 | 12 | 4.1 | |||
The Targets column indicates the number of proteins predicted as targets of the transcription factors. The NES (normalized enrichment score) column indicates the score of the enrichment prediction. Only transcription factors with a NES higher than four were considered.