Figure 6.
Oxidative mediated protein modifications, namely, 4-hydroxynonenal adducts (left), nitrotyrosine modifications (center) and protein carbonyl modifications (i.e. OxyBlot, right) for diaphragm samples from control, CLP, taurine and CLP + taurine groups. Top panels present representative Western blots for these modifications and bottom panels represent group mean data ± 1 SEM of protein densitometry for the modifications in each experimental group: control (black), CLP (red), sham + taurine (green) and CLP + taurine (blue) . CLP induced sepsis did not induce significant changes in the levels of any of these modifications and administration of taurine to sham or CLP operated animals did not alter levels of these three protein modifications.