Fig 1.
Study overview. First, two pairs of experienced radiologists individually performed a visual scoring of each scan’s PVP (portal venous phase) timing based on a three-point scoring system. Any scan with differing scores was reevaluated by both radiologists and a consensus score was reached. Using these values, a computer-aided scoring algorithm of the PVP timing (CASAPVP) was developed. Potentially misclassified PVP timings were detected by the CASAPVP and referred to the radiologists for a new consensus reading. The results of this new consensus reading then served as the reference standard for grading the accuracy of visual and computer scoring methods, as well as for studying the density variation of colorectal cancer with liver metastases due to PVP timing.