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. 2019 Nov 15;10:1341. doi: 10.3389/fphar.2019.01341

Table 1.

Biological activities of target compounds towards different cell lines.

Compds. IC50 (µM)a
A549 Hela HepG2 HL-60 WI-38
a1 107.35 ± 2.14 125.34 ± 6.92 134.64 ± 9.79 130.71 ± 5.38 229.04 ± 7.38
a2 82.46 ± 3.61 98.90 ± 2.90 76.96 ± 1.34 134.66 ± 2.45 122.2 ± 2.33
a3 59.59 ± 5.23 77.61 ± 4.74 71.21 ± 4.63 141.38 ± 5.19 126.24 ± 0.46
a4 48.17 ± 2.25 65.93 ± 7.80 46.41 ± 0.05 110.28 ± 2.04 100.24 ± 11.51
a5 57.25 ± 1.53 82.19 ± 4.80 68.13 ± 5.51 107.83 ± 3.50 127.04 ± 6.60
a6 51.34 ± 2.11 74.84 ± 2.33 75.41 ± 3.27 213.08 ± 2.98 109.48 ± 1.49
a7 40.72 ± 3.68 40.72 ± 1.33 55.62 ± 3.23 111.35 ± 1.57 81.70 ± 1.13
a8 64.95 ± 2.35 53.55 ± 0.67 57.35 ± 3.07 301.19 ± 3.53 147.31 ± 13.24
a9 57.63 ± 1.42 65.07 ± 1.34 80.31 ± 1.87 210.14 ± 3.03 98.46 ± 4.91
a10 45.55 ± 1.05 54.39 ± 1.11 70.80 ± 4.03 131.15 ± 4.64 93.28 ± 3.13
a11 35.84 ± 1.02 48.23 ± 0.56 44.71 ± 1.56 245.00 ± 5.54 89.48 ± 6.61
a12 41.22 ± 2.15 35.33 ± 2.13 54.37 ± 0.52 160.46 ± 3.59 122.98 ± 2.45
a13 37.62 ± 1.11 31.82 ± 1.62 50.33 ± 4.03 134.43 ± 4.44 117.69 ± 3.53
a14 36.70 ± 1.08 23.30 ± 2.35 38.33 ± 0.59 120.68 ± 3.58 121.29 ± 0.87
5-FUb 53.70 ± 1.16 35.21 ± 1.39 42.89 ± 2.88 165.13 ± 4.74 62.77 ± 2.03
a

IC50 values represent mean ± SE from at least three independent experiments.

b

Used as a reference.