Table 1.
Characteristics of individuals with PBC and control groups.
|
Primary biliary cholangitis (n = 36) |
Haemochromatosis (n = 31) |
Healthy controls (n = 9) |
p-value | |||
|---|---|---|---|---|---|---|
|
PBC vs. HFe |
PBC vs. HC |
HFe vs. HC |
||||
| Age at time of study, median (range) | 61 (44–83) | 51 (20–73) | 33 (20–40) | 0.002 | <0.001 | 0.007 |
| Men, N (%) Women, N (%) | 3 (8.3) 33 (91.7) | 24 (77.4) 7 (22.6) | 0 (0) 9 (100) | <0.001 | 0.370 | <0.001 |
| Cirrhosis, N (%) | 7 (19.4) | 7 (22.6) | 0 (0) | 0.753 | 0.150 | 0.117 |
| UDCA, N (%) | 28 (80.6) | 0 (0) | 0 (0) | <0.001 | <0.001 | - |
| Co-existent autoimmune disorder, N (%) | 9 (25.0) | 2 (6.5) | 0 (0) | 0.0410 | 0.094 | 0.434 |