Table 5.
Differences of imaging biomarkers among tumors with LF (or RF), DF, and NED.
|
Median DF (n = 12) |
Median LF (n = 10) |
Median NED (n = 30) |
KW test P value |
KW test P value with FDR |
WR test P value |
WR test P value with FDR |
|
|---|---|---|---|---|---|---|---|
| Primary tumor | |||||||
| TVBV pre | 11.37 | 24.24 | 7.10 | 0.06 | 0.3 | 0.08 | 0.3 |
|
DF (n = 17) |
LF (n = 8) |
NED (n = 57) |
KW test P value |
KW test P value with FDR |
WR test P value |
WR test P value with FDR |
|
| Nodal tumor | |||||||
| GTV pre | 8.68 | 32.14 | 5.78 | 0.01* | 0.1* | 0.07 | 0.5 |
| GTV 2 weeks | 6.57 | 24.94 | 3.97 | 0.02* | 0.1* | 0.08 | 0.5 |
| Change in GTV | −1.07 | −1.27 | −0.44 | 0.83 | 0.9 | 0.8 | 0.8 |
| TVBV pre | 2.77 | 4.77 | 1.77 | 0.02* | 0.1* | 0.2 | 0.5 |
| TVBV 2 weeks | 1.94 | 7.40 | 1.18 | 0.06 | 0.1 | 0.2 | 0.5 |
| Mean ADC pre | 1.38 | 1.40 | 1.19 | 0.06 | 0.1 | 0.9 | 0.9 |
| Mean ADC 2 weeks | 1.55 | 1.64 | 1.35 | 0.02* | 0.1* | 0.4 | 0.6 |
| Mean BV pre | 8.26 | 10.11 | 10.21 | 0.46 | 0.6 | 0.5 | 0.6 |
| Mean BV 2 weeks | 8.83 | 13.33 | 10.93 | 0.04* | 0.1 | 0.04* | 0.5 |
| Mean SUV of MTV50 pre | 3.91 | 5.38 | 2.35 | 0.02* | 0.1* | 0.3 | 0.5 |
| max SUV of MTV50 pre | 5.96 | 7.92 | 3.50 | 0.03* | 0.1 | 0.3 | 0.6 |
| TLG of MTV50 pre | 0.718 | 3.245 | 0.420 | 0.11 | 0.2 | 0.3 | 0.5 |
Tumor volume is a unit of cc. ADC is in unit of 10−3 mm2/s. BV is in unit of (ml/100 g). SUV of FDG is in unit of g/ml. TLG is in unit of 100 g.
Indicates significant.