. 2019 Sep 11;3(11):e10226. doi: 10.1002/jbm4.10226

Table 3.

Microstructure of Mineralized Trabecular Bone at the Metaphysis of the Femur

	6 Weeks		4 Months		18 Months		Two‐way ANOVA (p values)
	WT (n = 8 )	Shn3–/– (n = 8)	WT (n = 6)	Shn3–/– (n = 6)	WT (n = 8)	Shn3–/– (n = 8)	Inter action	geno type	Age
mdBV/TV (% )	18.33	43.41 ^a	7.10	54.91 ^a ^, ^c	5.87 ^c	47.55 ^a	.003	<.001	.301
mdBV/TV (% )	(3.35)	(8.58)	(3.35)	(10.97)	(3.44)	(14.37)	.003	<.001	.301
mdTb.Th. (μm)	38.69	51.04	34.73	126.1 ^a ^, ^b	51.60	105.3 ^a ^, ^b	<.001	<.001	<.001
mdTb.Th. (μm)	(4.48)	(10.12)	(7.47)	(32.68)	(27.37)	(34.85)	<.001	<.001	<.001
mdTh.N (1/mm)	4.74	8.69 ^a	1.99 ^b	4.41 ^a ^, ^b	1.19 ^b	4.61 ^a ^, ^b	.136	<.001	<.001
mdTh.N (1/mm)	(0.68)	(1.79)	(0.61)	(0.30)	(0.61)	(0.92)	.136	<.001	<.001

Data are mean (SD). n = number of studied mice. In bold: data that are significantly different to WT at similar age (based on Tukey post hoc comparison). Significance by Tukey post hoc comparison following two‐way ANOVA is indicated by superscript letters.

mdBV = mineralized bone volume per tissue volume; mdTb.Th. = mineralized trabecular thickness; mdTh.N = mineralized trabecular number.

p < .001 versus WT.

p < .001.

p < .05 versus 6 weeks (all based on Tukey post hoc comparison).