Table 2. Measured cytokine levels for patients before transarterial chemotherapy (D0) and at 3 days (D3), 7 days (D7), and 60 days (D60) post-transarterial chemotherapya.
D0 (n = 203) | D3 (n = 156) | D7 (n = 147) | D60 (n = 115) | |||||
---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
IL-12 | 11.46 | 53.95 | 8.95 | 46.52 | 10.86 | 46.71 | 25.48 | 130.98 |
IFN-γ | 34.02 | 165.42 | 24.05 | 142.76 | 30.33 | 171.63 | 21.16 | 99.06 |
IL-17α | 31.26 | 134.65 | 21.81 | 82.72 | 23.73 | 106.26 | 22.48 | 102.59 |
IL-2 | 98.68 | 774.16 | 44.45 | 122.68 | 43.53 | 133.72 | 40.15 | 122.75 |
IL-10 | 32.01 | 334.54 | 7.34 | 40.74 | 7.84 | 46.82 | 8.719 | 35.45 |
IL-9 | 12.43 | 83.41 | 7.71 | 35.66 | 7.79 | 31.23 | 20.85 | 77.88 |
IL-22 | 201.09 | 333.01 | 149.47 | 255.87 | 154.84 | 259.79 | 280.74 | 668.21 |
IL-6 | 4.77 | 16.22 | 14.44 | 40.36 | 9.32 | 24.56 | 56.16 | 495.97 |
IL-13 | 34.62 | 52.88 | 37.33 | 58.71 | 35.78 | 57.49 | 37.45 | 42.83 |
IL-4 | 40.31 | 123.77 | 34.95 | 89.99 | 33.75 | 100.49 | 39.24 | 97.95 |
IL-5 | 95.61 | 1212.58 | 9.56 | 67.06 | 11.08 | 86.32 | 7.51 | 76.49 |
IL-1β | 19.70 | 91.06 | 21.21 | 88.35 | 24.47 | 110.45 | 26.62 | 91.76 |
TNF-α | 26.11 | 138.56 | 29.84 | 133.78 | 29.22 | 175.53 | 24.67 | 117.66 |
CRPa | 19.45 | 37.14 | 38.67 | 41.21 | 32.62 | 44.19 | 26.93 | 43.72 |
IL, interleukin; IFN, interferon; TNF, tumor necrosis factor; CRP, C-reactive protein; SD, standard deviation.
aStatistical analysis was performed using a Kruskal-Wallis test for analysis of variance among D0, D3,D7and D60 and only CRP revealed statistical significance. Units for cytokines are as follows: CRP, mg/L; others, pg/mL.