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. 2019 Dec;25(12):2284–2286. doi: 10.3201/eid2512.190012

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This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Whole-genome sequencing phylogenetic relationship of genotype 10:u isolates of Mycobacterium bovis from 1 human, 7 cats, 11 cattle, and 1 alpaca, and 10:a isolates from 3 cattle (maximum-likelihood tree of all single-nucleotide polymorphisms [SNPs]). Cat and human isolates are indicated by solid arrowheads. Heat-killed cultures were sequenced by using a MiSeq Sequencer (Illumina, https://www.illumina.com), and reads were mapped by using reference strain AF2122. The average coverage ranged from 23.9-fold to 88.8-fold. The human and their household cat contact (cat 5) isolates were indistinguishable in their genome sequences. Scale bar indicates SNPs.