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Status of the E4 11-kDa and 34-kDa genes and DNA replication phenotypes in the viruses studied.
| Virus | E4-11kDa gene status (E4 ORF3) | E4-34kDa gene status (E4 ORF6) | DNA replication* |
|---|---|---|---|
| Ad5 | + | + | 1 |
| E4- | − | − | 0.19 |
| 1010 | + | − | 0.84 |
Measured by Southern blotting of total DNA prepared from cells infected at an MOI of 3FFU/cell. Values are expressed as the fraction of the Ad5 value as determined by densitometry.
